2018 – Clean3

20 Dec 2018

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2019 PDA Annual

PDA’s flagship Annual Meeting provides a venue for obtaining the latest and most comprehensive information on a broad range of topics related to processing, manufacturing, supply chain and quality control. Moreover, the meeting provides a venue for learning, benchmarking and sharing of learnings with respect to innovation and continuous improvement, ultimately providing quality medicines for patients.

The theme of the 2019 meeting is Solving Manufacturing and Supply Challenges for Current and Future Medicinal Products. In selecting this theme, the planning committee’s goal is to design a comprehensive event that encompasses the wide-ranging interests of all PDA members. Whether you are focused on improving existing processes or delving into entirely new technologies and therapies, we will cover relevant information important to both small molecule pharmaceutical and biopharmaceutical industries will be covered.

18 Dec 2018

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2019 ISPE Aseptic

2019 ISPE Aseptic Conference: Next Steps in Future of Aseptic Processing: Containment, Multi-Product Facilities, & Robotics. The 2019 ISPE Aseptic Conference, now in its 28th year, focuses on the future of aseptic processing, including containment, multi-product facilities, and the increasing use of robotics. Join us as leading industry and regulatory experts explore the latest developments.

15 Nov 2018

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2019 PACK EXPO

Pack EXPO Las Vegas Powers Innovation in Packaging – With 30,000 attendees and 2,000+ exhibitors, PACK EXPO Las Vegas and co-located Healthcare Packaging EXPO will be the largest packaging trade show in the world in 2019. The show will feature a co-located 900,000 net square-foot show floor with packaging machinery in action, Free educational sessions for attendees in venues on the show floor, Pavilions for Containers and Materials, Confectionery and Reusable Packaging. Also, new to Las Vegas – The PACKage Printing Pavilion for printing and converting technologies. READ MORE

13 Nov 2018

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AWS Bio-Pharma Technologies Partners with M&O Perry

AWS Bio-Pharma Technologies announces their expanded partnership with M&O Perry (MOP), who specializes in aseptic powder & liquid filling and plastic syringe tip-filling equipment. While AWS and MOP have collaborated regularly through the years, we are committed to work even more closely going forward as both AWS & MOP continue to grow. Over the years, we have enjoyed working with MOP both as a client and a vendor. Additionally, MOP provides Parenteral Fillers, Cappers, Washers and Depyrogenation Tunnels for Pharmaceutical Processing. Our strategic partnerships with other pharmaceutical processing equipment manufacturers allow us to provide fully customized processing systems and cleanroom space, realized in our CLEAN³ Turn-key Systems which AWS Bio-Pharma Technologies exclusively distributes under the CLEAN³ Modular Systems brand.

13 Jun 2018

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Inspection Systems – BM Series

Convel’s BM Series Automatic Inspection System is used to detect particles and leaks in plastic bags. Other options include integrating a labeler or cosmetic controls.

DESCRIPTION

The operator positions the bags over an infeed belt between the slots. A pneumatic arm automatically collects the containers one at a time and positions them between the turret pinces. The turret moves intermittently through the four stations, each one performing a different test. The first station uses the high voltage method to perform the leak test. Next, the second and third stations both inspect the bags for foreign matter. Then the final station labels the plastic bags. The rejected bags are automatically expelled, while the accepted bags continue on toward the outfeed belt.

ADVANCED FEATURES

Leak Test: Performs using high voltage (up to 35KV with frequency around 1000 Hz). Fast and efficient, which prevents product degradation and contamination

Leak test area: Surrounds the inlet gates and bottom welding

Foreign Matter Inspection: Each station is equipped with up to 4 cameras (color or B/W)

Detectable Particles: Fibers, dark particles and clear plastic particles

Special Features: A set of in-built connectors automatically checks electronics which performs the leak test and ozone evacuation, the Illumination system uses long life LED lights (in different colors), cGMP compliant, User friendly HMI with a 17” touchscreen and Windows PC with full audit trail functions and several levels of passwords

Additional Controls: Flip-off Inspection, Label Presence Inspection, OCR-OCV and Bar Code Inspection. Other options available upon request.

READ MORE ABOUT OUR INSPECTION SYSTEMS

13 Jun 2018

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Nested Filling Lines – RNFM Series

Our RNFM Series, Robotic Nested Filler are linear style fillers which process syringes, cartridges, and vials (nested) from 1ml to 30mm in diameter with production speeds up to 200 units/minute, with minimal format changes.

METHOD OF OPERATION

Tubs of nest empty glassware are positioned into the RNFM and the outer wrap and lid are automatically removed from the tub of the nested empty glassware. After lid removal the tube of empty syringes (cartridges or vials) will be placed automatically into the in-feed position of the filling and stoppering system. The system has two working platforms with a centering frame. A manipulator arm with vacuum gripper automatically takes the nest out of the tub and places it into one of the two nest indexing platforms. The platform moves the nest lengthwise and laterally into an exact position under the filling needles and stopper insertion tubes. Both the individual centering of each syringe in the frame, as well as the precisely controlled movement of the platform under the working stations ensure that any friction of tools against the syringes are avoided. While the filling and stoppering of the first nest is going on, another nest with empty syringes will be picked up by the vacuum gripper, and will be placed into the second nest indexing platform.

FEATURES

Conveyor belt to transfer the tubs from an optional de-liner system into the nest filling system
Vacuum gripper device to remove the nest from the tub and place it into the nest indexing platform
Two fully automatic nest indexing platforms, with alternating positions at filling/stoppering area and loading/unloading area, to move nest lengthwise and laterally into exact position under filling needles and stoppering vent tubes
Two three-point centering frames with centering plates adjusted to clamp 1 size of syringe in defined position in the nest, made of SST with PE guide for the centering plates, set up for one syringe format
One check station to verify if nest has been correctly inserted into centering frame
One servo controlled bottom up filling movement.
One servo-controlled filling station for rotary piston pumps including a main servo drive and central fill volume adjustment via format menu in the HMI
One set of dosing size parts (ANSI 316 stainless steel), including filling hoses and filling needles.
One glass buffer tank with min. and max level sensor and valve to connect to customer’s main product tank. (The buffer tank is located on the system next to the filling station and will ensure the same pressure level of product supply in relation to the filling nozzles and will therefore enable the filler to achieve a filling accuracy of greater than ± 0.5 % for fill volume > 1 ml)
One product manifold (ANSI 316 L) to connect to the pumps
One fully automatic vent tube/push rod type stoppering station with vibratory plunger stopper un-scrambler bowl with vibratory multi-lane feed track adjusted for one size of stopper/plug
Nest transfer system consisting of one conveyor open system for tub discharge up to wall inside the filling room and 1 roller conveyor (approx. 1 mtr. long) for tub collection outside filling room
Parts above open syringes and stoppers that could hamper the laminar flow are minimized
Dead zones for cleaning are eliminated; all surfaces exposed to the working area are well accessible for cleaning
Format parts are easy to dismantle and mount under aseptic conditions and the use of tools for format change over is avoided
Minimization of idle time between two nests by using two alternating centering platforms
Also consider our Robotic UV Sterilizing System for tub sterilization

13 Jun 2018

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CIP-SIP Systems – Mobile CIP-SIP Model

Bram-cor’s CIP-SIP Systems are designed to fully meet cGMP requirements for cleaning and sterilizing practices commonly applied in pharmaceutical process tanks, lines and systems. Bram-Cor CIP/SIP systems are supplied as fixed stations or mobile skids with manual, semi-automatic or automatic control systems. Our CIP/SIP systems and be powered by electric heater, industrial steam, or combination units.

CLEANING PARAMETERS FOR CIP/SIP SYSTEMS

Contact time of solution
CIP supply temperature
CIP return temperature
Chemical conductivity (pH)for wash solutions
Final rinse resistivity (pH)for wash solutions
Supply pressure
Tanks levels

2018 PACK EXPO International

Attendees include corporate, general, plant and project managers; engineers; production supervisors; those involved in operations and quality control; purchasers; package designers, brand managers and marketers; and logistics and supply chain management professionals from all vertical industries. Exhibitors include 2,500+ leading suppliers of advanced packaging equipment, materials, containers, automation technologies and other supply chain solutions. New in 2018, the PACKage Printing Pavilion is bringing together suppliers of the latest digital packaging solutions.

02 May 2018

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Traditional Aseptic Fillers – Complete Compact Filling Line

A complete compact system for processing vials, cartridges, syringes or ampoules. The system includes a Rotary Washer, Depyrogenation Tunnel, Filler/Stoppering/Capper System and Isolator or RABS. Our Complete Compact Filling line features the smallest foot print in the world, suitable for clinical manufacturing, laboratory and R and D applications. With a small foot print (less than 15 feet long), the only thing big about this system is the energy saving features it offers. Several models and options are available for a customized solution to your specific application.

Steriline’s RA Series Rotary Washers utilize typical European style gripper mechanisms to handle the glassware, ensuring thorough and consistent washing. The washer is equipped with needles which are lifted to penetrate the glassware and then spray the appropriate washing and drying fluids. After washing, the glassware is up-righted and directly discharged onto the Depyrogenation Tunnel.

The vials pass through the inlet chamber then enter the hot chamber where the depyrogenation process takes place. The glassware then enters the cooling chamber to cool down to a suitable temperature before discharge onto the rotary in-feed table of the filler. The filler can be equipped for any type of pump with several purging options. The filler and capper are separated to ensure process control over the separate functions. After filling, the vials can be immediately capped or removed for Lyophilization. Many options are available, including the ability to capper vials after lyophilization, 21 CFR Part 11 compliance, sterilizable cooling zone, various enclosure types over the filler, etc. An exterior vial washer is also available to ensure the safety of your workers in downstream packaging areas. The depyrogenation tunnel has the added advantage of the air being recycled in each of the three chambers due to the absence of intake and exhaust ducts in the hot zone. The pressure differential between the cooling chamber and the inlet chamber allows for approximately 100 air changes per hour in each chamber. The highly accurate automatic control of air speed in the chambers and of the pressure control inside the tunnel has always been one of the greatest advantages of Steriline’s depyrogenation tunnels. Combine the compact line with other processing options and modular cleanrooms.

26 Apr 2018

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AWS’ New Vice President of Sales

AWS is pleased to announce that Chris Wernimont has joined our sales team here in North America as VP of Sales. Chris will be based in the Indianapolis area and will be responsible for sales primarily in the Midwestern region of the US. Likewise, he has many years of experience in pharma and is very excited to work with our team on our diverse range of aseptic filling products and support systems. In addition to his experience, Chris enjoys a well-earned solid reputation in our industry for being very knowledgeable and honest. Moreover, he is highly dedicated to delivering the best possible solution to each and every client.

In the near future, Chris will be visiting all our partners to develop a better understanding of their equipment offerings. Further, he will have the opportunity to meet their staff and gain an overall sense of their capabilities and goals. Please join us in welcoming Chris to AWS Bio-Pharma Technologies and feel free to reach out to him at any time.

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